DES Follow-up Study Published Papers


A Prospective Cohort Study of Prenatal Diethylstilbestrol Exposure and Cardiovascular Disease Risk. Troisi R, Titus L, Hatch EE, Palmer JR, Huo D, Strohsnitter WC, Adam E, Ricker W, Hyer M, Hoover RN. J Clin Endocrinol Metab. 2018 Jan 1;103(1):206-212. doi: 10.1210/jc.2017-01940. [Summary of A Prospective Cohort Study of Prenatal Diethylstilbestrol Exposure and Cardiovascular Disease Risk.]

Prenatal diethylstilbestrol exposure and risk of obesity in adult women.Hatch EE, Troisi R, Palmer JR, Wise LA, Titus L, Strohsnitter WC, Ricker W, Hyer M, Hoover RN. J Dev Orig Health Dis. 2015 Jun;6(3):201-7. [Summary of Prenatal diethylstilbestrol exposure and risk of obesity in adult women]

Menarche, menopause, years of menstruation, and the incidence of osteoporosis: the influence of prenatal exposure to diethylstilbestrol. Parker SE, Troisi R, Wise LA, Palmer JR, Titus-Ernstoff L, Strohsnitter WC, Hatch EE. J Clin Endocrinol Metab 2014;99:594-601. [Summary of Menarche, menopause, years of menstruation, and the incidence of osteoporosis]

Prenatal DES exposure in relation to breast size. Palmer JR, Boggs DA, Hatch EE, Troisi R, Titus-Ernstoff L, Strohsnitter WC, Adam E, Hoover RN. Cancer Cause Control. 2013;24:1757-61. [Summary of Prenatal DES exposure in relation to breast size]

Medical conditions among adult offspring prenatally exposed to diethylstilbestrol. Troisi, R., Hyer, M., Hatch, E.E., Titus-Ernstoff, L., Palmer, J.R., Strohsnitter, W.C., Herbst, A.L., Adam, E., Hoover, R.N., Epidemiology 2013 May; 24(3):430-8.[Summary of Medical conditions among adult offspring prenatally exposed to diethylstilbestrol]

Lifetime burden of adverse health outcomes among women exposed in-utero to Diethylstilbestrol (DES). Hoover, R.N., Hyer, M., Pfeiffer, R.M., Adam, E., Bond, B., Cheville, A.L., Colton, T., Hartge, P., Hatch, E.E., Herbst, A., Karlan, B.Y., Kaufman, R., Noller, K.L., Palmer, J.R., Robboy, S.J., Saal, R.C., Strohsnitter, W., Titus-Ernstoff, L., Troisi, R. N Engl J Med. 2011;365:1304-14. [Summary of Lifetime burden of adverse health outcomes among women exposed in-utero to Diethylstilbestrol (DES)]

Preterm Birth, Birth Weight and Age at Menarche among Women Exposed Prenatally to Diethylstilbestrol (DES). Hatch, E.E., Troisi, R., Wise, L.A., Titus-Ernstoff, L., Hyer, M., Palmer, J.R., Strohsnitter, W.C., Robboy, S.J., Anderson, D., Kaufman, R., Adam, E., Hoover, R.N. Reprod Toxicol 2011;31:151-7. [Summary of reterm Birth, Birth Weight and Age at Menarche among Women Exposed Prenatally to Diethylstilbestrol (DES)]

Autoimmune disease incidence among women prenatally exposed to diethylstilbestrol. Strohsnitter, W.C., Noller, K.L, Troisi, R., Robboy, S.J, Hatch, E.E., Titus-Ernstoff, L., Kaufman, R.H., Palmer, J.R., Anderson, D., Hoover, R.N. J Rheumatol. 2010;37:2167-73. [Summary of Autoimmune disease incidence among women prenatally exposed to diethylstilbestrol]

Birth defects in the sons and daughters of women who were exposed in utero to Diethylstilbestrol (DES). Titus-Ernstoff, L., Troisi, R., Hatch, E.E., Palmer, J.R., Hyer, M., Kaufman, R., Adam, E., Knoller, K., Hoover, R.N. Int J Androl 2009. Int J Androl. 2010;33:377-84. [Summary of Birth defects in the sons and daughters of women who were exposed in utero to Diethylstilbestrol (DES)]

Urogenital Abnormalities in Men Exposed to Diethylstilbestrol in Utero. Palmer, J.R., Herbst, A.L., Noller, K.L., Boggs, D.A., Troisi, R., Titus-Ernstoff, L., Hatch, E.E., Wise, L.A., Strohsnitter, W.C., Hoover, R.N Environ Health 2009;8:37. [Summary of Urogenital Abnormalities in Men Exposed to Diethylstilbestrol in Utero]

Breast Cancer Screening in Women Exposed In Utero to Diethylstilbestrol, Elizabeth A. Camp, Ann L. Coker, Stanley J. Robboy, Kenneth L. Noller, Karen J. Goodman, Linda T. Titus-Ernstoff, Elizabeth E. Hatch, Arthur L. Herbst, Rebecca Troisi, Raymond H. Kaufman, Ervin Adam. Journal of Women's Health 2009;18:547-552. [Summary of Breast Cancer Screening in Women Exposed In Utero to Diethylstilbestrol]

Cervical Screening and General Physical Exam Behaviors of Women Exposed In-utero to Diethylstilbestrol. Camp EA, Coker AL, Troisi R, Robboy SJ, Noller KL, Goodman K, Titus-Ernstoff L, Hatch EE, Herbst AL, Kaufman RH, Adam E. Journal of Lower Genital Tract Disease 2008;12:111-7. [Summary of Cervical Screening and General Physical Exam Behaviors of Women Exposed In-utero to Diethylstilbestrol]

Offspring of Women Exposed In Utero to Diethylstilbestrol (DES): A Preliminary Report of Benign and Malignant Pathology in the Third Generation. Titus-Ernstoff L, Troisi R, Hatch EE, Hyer M, Wise LA, Palmer JR, Kaufman R, Adam E, Noller K, Herbst AL, Strohsnitter W, Cole BF, Hartge P, Hoover RN. Epidemiology 2008;19:251-257 [Summary of Offspring of Women Exposed In Utero to Diethylstilbestrol (DES)]

The association between in utero cigarette smoke exposure and age at menopause. Strohsnitter WC, Hatch EE, Hyer M, Troisi R, Kaufman RH, Robboy SJ, Palmer JR, Titus-Ernstoff L, Anderson D, Hoover RN, Noller KL. Epidemiology 2008;167:727-733. [Summary of The association between in utero cigarette smoke exposure and age at menopause]

Time to pregnancy and secondary sex ratio in men exposed prenatally to diethylstilbestrol. Wise L, Titus-Ernstoff L, Palmer JR, Hatch EE, Perez KM, Strohsnitter W, Kaufman R, Anderson D, Hoover RN, Troisi R. Am J Epidemiol 2007;166:765-74. [Summary of Time to pregnancy and secondary sex ratio in men exposed prenatally to diethylstilbestrol]

Secondary sex ratio among women exposed to diethylstilbestrol in utero. Wise LA, Palmer JR, Hatch EE, Troisi R, Titus-Ernstoff L, Herbst AL, Kaufman R, Noller KL, Hoover RN. Environ Health Perspect. 2007;115:1314-9. [Summary of Secondary sex ratio among women exposed to diethylstilbestrol in utero]

Preeclampsia risk in women exposed in utero to diethylstilbestrol. Troisi R, Titus-Ernstoff L, Hyer M, Hatch EE, Robboy SJ, Strohsnitter W, Palmer JR, Øgloend B, Adam E, Kaufman R, Herbst AL, Hoover RN. Obstet Gynecol. 2007 Jul;110(1):113-20 [Summary of Preeclampsia risk in women exposed in utero to diethylstilbestrol]

Cancer risk in women prenatally exposed to diethylstilbestrol. Troisi R, Hatch EE, Titus-Ernstoff L, Hyer M, Palmer JR, Robboy SJ, Strohsnitter WC, Kaufman R, Herbst AL, Hoover RN. Int J Cancer. 2007 Jul 15;121(2):356-60 [Summary of Cancer risk in women prenatally exposed to diethylstilbestrol]

Menstrual and reproductive characteristics of women whose mothers were exposed in utero to diethylstilbestrol (DES). Titus-Ernstoff L, Troisi R, Hatch EE, Wise LA, Palmer J, Hyer M, Kaufman R, Adam E, Strohsnitter W, Noller K, Herbst AL, Gibson-Chambers J, Hartge P, Hoover RN. Int J Epidemiol. 2006 Aug;35(4):862-8. Epub 2006 May 24. [Summary of Menstrual and reproductive characteristics of women whose mothers were exposed in utero to diethylstilbestrol (DES)]

Mortality in women given diethylstilbestrol during pregnancy. Titus-Ernstoff L, Troisi R, Hatch EE, Palmer JR, Wise LA, Ricker W, Hyer M, Kaufman R, Noller K, Strohsnitter W, Herbst AL, Hartge P, Hoover RN. Br J Cancer. 2006 Jul 3;95(1):107-11. [Summary of Mortality in women given diethylstilbestrol during pregnancy]

Age at natural menopause in women exposed to diethylstilbestrol in utero. Hatch EE, Troisi R, Wise LA, Hyer M, Palmer JR, Titus-Ernstoff L, Strohsnitter W, Kaufman R, Adam E, Noller KL, Herbst AL, Robboy S, Hartge P, Hoover RN. Am J Epidemiol. 2006 Oct 1;164(7):682-8. [Summary of Age at natural menopause in women exposed to diethylstilbestrol in utero]

Prenatal diethylstilbestrol exposure and risk of breast cancer. Palmer JR, Wise LA, Hatch EE, Troisi R, Titus-Ernstoff L, Strohsnitter W, Kaufman R, Herbst AL, Noller KL, Hyer M, Hoover RN. Cancer Epidemiol Biomarkers Prev; 2006 Aug;15(8):1509-14. [Summary of Prenatal diethylstilbestrol exposure and risk of breast cancer]

Birth Weight and Breast Cancer Risk in Women Exposed and Unexposed to DES In Utero. Troisi R, Hatch EE, Titus-Ernstoff L, Palmer JR, Hyer M, Strohsnitter W, Robboy SJ, Kaufman RH, Herbst AL, Adam E, Hoover RN. Br J Cancer 2006;94:1734-7. [Summary of Birth Weight and Breast Cancer Risk in Women Exposed and Unexposed to DES]

In utero exposure to diethylstilbestrol (DES) does not increase genomic instability in normal or neoplastic breast epithelium. Larson PS, Ungarelli RA, de Las Morenas A, Cupples LA, Rowlings K, Palmer JR, Rosenberg CL. Cancer. 2006;107:2122-6. [Summary of In utero exposure to diethylstilbestrol (DES) does not increase genomic instability in normal or neoplastic breast epithelium]

Hypospadias in male offspring of women exposed to diethylstilbestrol in utero. Palmer JR, Wise LA, Robboy SJ, Titus-Ernstoff L, Noller KL, Herbst AL, Troisi R, Hoover RN. Epidemiology. 2005 Jul;16(4):583-6. [Summary of Hypospadias in male offspring of women exposed to diethylstilbestrol in utero]

Risk of benign gynecologic tumors in relation to prenatal diethylstilbestrol exposure. Wise LA, Palmer JR, Rowlings K, Kaufman RH, Herbst AL, Noller KL, Titus-Ernstoff L, Troisi R, Hatch EE, Robboy SJ. Obstet Gynecol (2005;105:167-73) [Summary of Risk of benign gynecologic tumors in relation to prenatal diethylstilbestrol exposure]

Breast cancer incidence in women prenatally exposed to maternal cigarette smoke. Strohsnitter WC, Noller KL, Titus-Ernstoff L, Troisi R, Hatch EE, Poole C, Glynn RJ, Hsich C-c. Epidemiology 2005;16(3):242-5 [Summary of Breast cancer incidence in women prenatally exposed to maternal cigarette smoke]

Reproductive outcomes in men with prenatal exposure to diethylstilbestrol. Perez KM, Titus-Ernstoff L, Hatch EE, Troisi R, Wactawski-Wende J, Palmer JR, Noller K, Hoover RN; National Cancer Institute's DES Follow-up Study Group. Fertil Steril 2005;84:1649-56. [Summary of Reproductive outcomes in men with prenatal exposure to diethylstilbestrol]

Psychosexual characteristics of men and women exposed prenatally to Diethylstilbestrol. Titus-Ernstoff L, Perez K, Hatch EE, Troisi R, Palmer JR, Hartge P, Hyer M, Kaufman R, Adam E, Strohsnitter W, Noller K, Pickett K, Hoover R. Epidemiology 2003;14:155-60. [Summary of Psychosexual characteristics of men and women exposed prenatally to Diethylstilbestrol]

Risk of breast cancer in women exposed to diethylstilbestrol in utero: preliminary results (United States). Palmer JR, Hatch EE, Rosenberg CL, Hartge P, Kaufman RH, Titus-Ernstoff L, Noller KL, Herbst AL, Rao RS, Troisi R, Colton T, Hoover RN. Cancer Causes Control 2002;13:753-8. [Summary of Risk of breast cancer in women exposed to diethylstilbestrol in utero: preliminary results (United States)]

Findings in female offspring of women exposed in-utero to diethylstilbestrol. Kaufman RH and Adam E. Obstet Gynecol 2002;99:197-200. [Summary of Findings in female offspring of women exposed in-utero to diethylstilbestrol]

Incidence of squamous neoplasia of the cervix and vagina in women exposed prenatally to diethylstilbestrol (United States). Hatch EE, Herbst AL, Hoover RN, Noller KL, Adam E, Kaufman RH, Palmer JR, Titus-Ernstoff L, Hyer M, Hartge P, Robboy SJ. Cancer Causes Control 2001;12:837-45. [Summary of Incidence of squamous neoplasia of the cervix and vagina in women exposed prenatally to diethylstilbestrol (United States)]

Long-term cancer risk in women given diethylstilbestrol (DES) during pregnancy. Titus-Ernstoff L, Hatch EE, Hoover RN, Palmer J, Greenberg ER, Ricker W, Kaufman R, Noller K, Herbst AL, Colton T, Hartge P. Brit J Cancer 2001;84(1):126-133. [Summary of Long-term cancer risk in women given diethylstilbestrol (DES) during pregnancy]

Cancer risk in men exposed in utero to diethylstilbestrol. Strohsnitter WC, Noller KL, Hoover RN, Robboy SJ, Palmer JR, Titus-Ernstoff L, Kaufman RH, Adam E, Herbst AL, Hatch EE. J Natl Cancer Inst 2001;93(7):545-51. [Summary of Cancer risk in men exposed in utero to diethylstilbestrol]

Infertility among Women Exposed Prenatally to Diethylstilbestrol. Palmer JR, Hatch EE, Rao RS, Kaufman RH, Herbst AL, Noller KL, Titus-Ernstoff L, Hoover RN. Am J Epidemiol 2001;154(4):316-321. [Summary of Infertility among Women Exposed Prenatally to Diethylstilbestrol]

Continued follow-up of pregnancy outcomes in diethylstilbestrol-exposed offspring. Kaufman RH, Adam E, Hatch EE, Noller K, Herbst AL, Palmer JR, Hoover RN. Obstet Gynecol 2000;96(4):483-9. [Summary of Continued follow-up of pregnancy outcomes in diethylstilbestrol-exposed offspring]

Incidence of squamous neoplasia of the cervix and vagina in DES-exposed daughters. Hatch EE, Herbst AL, Hoover RN, Noller KL, Adam E, Kaufman RH, Palmer JR, Titus-Ernstoff L, Hyer M, Hartge P, Robboy SJ. Ann Epidemiol 2000;10(7):467. [Summary of Incidence of squamous neoplasia of the cervix and vagina in DES-exposed daughters]

Cancer risk in women exposed to diethylstilbestrol in utero. Hatch EE, Palmer JR, Titus-Ernstoff, Noller KL, Kaufman RH, Mittendorf R, Robboy SJ, Hyer M, Cowan CM, Adam E, Colton T, Hartge P, Hoover RN. JAMA 1998;280(7):630-4. [Summary of Cancer risk in women exposed to diethylstilbestrol in utero.]